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United States and its territories. Indications, uses and warnings on Drugs. Cialis tadalafil Australian prescribing information. Alfuzosin undergoes extensive metabolism by the liver, with only 11% of the administered dose excreted unchanged in the urine. Alfuzosin is metabolized by three metabolic pathways: oxidation, O-demethylation, and N-dealkylation. The metabolites are not pharmacologically active. CYP3A4 is the principal hepatic enzyme isoform involved in its metabolism. Floppy iris syndrome: Intraoperative floppy iris syndrome has been observed in cataract surgery patients who were on or were previously treated with alpha 1-blockers; there appears to be no benefit in discontinuing alpha 1-blocker therapy prior to surgery. May require modifications to surgical technique. safeway brand mebendazole

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Administer immediately following a meal at the same time each day. Swallow tablet whole; do not crush or chew. Tell your doctor if your condition does not improve or if it worsens such as your remain high or increase. Mitotane: May decrease the serum concentration of CYP3A4 Substrates. Management: Doses of CYP3A4 substrates may need to be adjusted substantially when used in patients being treated with mitotane.

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Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with not feel sick. It may have something to do with genetics or age. It's also possible that the sleeplessness or that can come from an enlarged prostate makes sexual problems worse. Treatment could include proper cleaning, medication, or surgery. They get tired and need to rest, just like any other part of your body.

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If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Grapefruit juice may increase the amount of your prostate medicine in your blood. If symptoms of angina pectoris should appear or worsen, alfuzosin HCl extended-release tablets should be discontinued. People with immune system conditions like AIDS, rheumatoid arthritis, or ulcerative colitis may be more likely to have uveitis.



Dry mouth is common with these medicines

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Difficulty starting to urinate. The pharmacokinetics of UROXATRAL have not been studied in patients with mild hepatic impairment. Some medicines can interact with alfuzosin and should not be used at the same time. Protease Inhibitors: May increase the serum concentration of Alfuzosin. Some medicines can interact with Genvoya and should not be used at the same time. Angina: Discontinue if symptoms of angina occur or worsen. Genvoya is not expected to be harmful to an unborn baby. However, HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection. Some stay small and don't affect your sight. If they do progress and affect your vision, surgery almost always works to bring it back. Table 3. Mean QT and QTc changes in msec 95% CI from baseline at T m a x relative to placebo with different methodologies to correct for effect of heart rate.



What should i avoid while taking alfuzosin

Alfuzosin may cause a condition that affects the heart rhythm QT prolongation. This medication may interfere with certain laboratory tests including glucose tolerance testing possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. Ask your doctor or pharmacist if you are not sure if your medicine is one of those listed above. AUC of unbound drug in females and males, respectively. The highest dose tested in female mice may not have constituted a maximally tolerated dose. RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. These medicines calm the nerves that control muscles. They may prevent uncontrollable bladder that force urine out of the bladder. HCl. The molecular weight of alfuzosin hydrochloride is 425. UROXATRAL 10 mg daily. Table 4 provides the results of the three trials that evaluated the 10 mg dose. Alfuzosin showed no evidence of mutagenic effect in the Ames and mouse lymphoma assays, and was free of any clastogenic effects in the Chinese hamster ovary cell and in vivo mouse micronucleus assays. Alfuzosin treatment did not induce DNA repair in a human cell line. Kevin T. McVary, MD, urology professor at Southern Illinois University School of Medicine. Levitra vardenafil hydrochloride US prescribing information. St John's Wort: May decrease the serum concentration of CYP3A4 Substrates. Management: Consider an alternative for one of the interacting drugs. Some combinations may be specifically contraindicated. Consult appropriate manufacturer labeling. Following oral administration of 14C-labeled alfuzosin solution, the recovery of radioactivity after 7 days expressed as a percentage of the administered dose was 69% in feces and 24% in urine. Following oral administration of UROXATRAL 10 mg tablets, the apparent elimination half-life is 10 hours. geodon



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If you have hepatitis B you may develop liver symptoms after you stop taking this medicine, even months after stopping. Your doctor may want to check your liver function for several months after you stop using Genvoya. Palbociclib: May increase the serum concentration of CYP3A4 Substrates. Patients should be advised not to crush or chew UROXATRAL tablets. This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. If you have an eye surgery for cataract clouding of the eye planned, tell your ophthalmologist that you are using alfuzosin hydrochloride extended-release tablets or have previously been treated with an alpha-blocker. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of this medicine on the baby. Take alfuzosin hydrochloride extended-release tablets exactly as your doctor prescribes them. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. If your feel strained, give them some time off. cheap hydroxyurea purchase payment uk hydroxyurea



How do I store UROXATRAL?

How do I store UROXATRAL? Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended. As illustrated in Figure 1, the extent of absorption is 50% lower under fasting conditions. Flomax tamsulosin hydrochloride US prescribing information. Fosaprepitant: May increase the serum concentration of CYP3A4 Substrates. In these 3 trials, 473 men received UROXATRAL alfuzosin HCl 10 mg extended-release tablets. In these trials, 4% of patients taking UROXATRAL alfuzosin HCl 10 mg extended-release tablets withdrew from the trial due to adverse reactions, compared with 3% in the placebo group. McVary and several colleagues recently did a study of this treatment and found promising results. Not only did it help improve BPH symptoms, but it kept sexual function intact. How do I take alfuzosin HCl extended-release tablets? Go to the emergency room or call 911. Carcinoma of the prostate and benign prostatic hyperplasia BPH cause many of the same symptoms. These two diseases frequently coexist. Therefore, patients thought to have BPH should be examined to rule out the presence of carcinoma of the prostate prior to starting treatment with alfuzosin HCl extended-release tablets. Of the total number of subjects in clinical studies of UROXATRAL, 48% were 65 years of age and over, whereas 11% were 75 and over. Bayer, Inc. October 24, 2006. UROXATRAL is indicated for the treatment of signs and symptoms of benign prostatic hyperplasia. Genvoya is for use in adults and children who are at least 12 years old. Patients should be told about the possible occurrence of symptoms related to postural hypotension, such as dizziness, when beginning UROXATRAL, and they should be cautioned about driving, operating machinery, or performing hazardous tasks during this period. UROXATRAL alfuzosin HCl extended-release tablet 10 mg is available as a round, three-layer tablet: one white layer between two yellow layers, debossed with X10. store oxytrol usage



Alfuzosin ingredients

Genvoya may increase your risk of certain infections or autoimmune disorders by changing the way your immune system works. Symptoms may occur weeks or months after you start treatment. If you continue to have problems with dry after a couple of weeks, call your doctor. This information is generalized and not intended as specific medical advice. Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. If your problem is chronic, you may have dry eye disease. You doctor could prescribe medicated drops like or lifitegrast to stimulate tear production. Rarely, in severe cases, extreme dryness can lead to some loss of vision. Moderate Risk QTc-Prolonging Agents: QTc-Prolonging Agents Indeterminate Risk and Risk Modifying may enhance the QTc-prolonging effect of Moderate Risk QTc-Prolonging Agents. Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day. If any of these effects persist or worsen, tell your doctor or promptly. Some people taking Genvoya develop a serious condition called lactic acidosis. Other, more serious conditions also happen as you age. Inactive Ingredients: colloidal silicon dioxide NF ethylcellulose NF hydrogenated castor oil NF hydroxypropyl methylcellulose USP magnesium stearate NF mannitol USP microcrystalline cellulose NF povidone USP and yellow ferric oxide NF. QTdrugs List, AZCERT, Inc. If you have hepatitis B you may develop liver symptoms after you stop taking this medicine. Your doctor may want to check your liver function for several months. If you have an eye surgery for cataract clouding of the eye planned, tell your ophthalmologist that you are using alfuzosin HCl extended-release tablets or have previously been treated with an alpha-blocker. Dizziness or lightheadedness may occur. If either of these effects persists or worsens, tell your doctor or pharmacist promptly.



Common side effects of alfuzosin

Patients should be advised about the possibility of priapism resulting from treatment with UROXATRAL and medications in the same class. The concomitant administration of the two drugs showed an increased QT effect when compared with either drug alone. Each UROXATRAL extended-release tablet contains 10 mg alfuzosin hydrochloride as the active ingredient. QT prolongation: Alfuzosin has been shown to prolong the QT interval alone minimal and with other drugs with comparable effects on the QT interval additive. Use with caution in patients with known QT prolongation congenital or acquired. Enzalutamide: May decrease the serum concentration of CYP3A4 Substrates. Management: Concurrent use of enzalutamide with CYP3A4 substrates that have a narrow therapeutic index should be avoided. Use of enzalutamide and any other CYP3A4 substrate should be performed with caution and close monitoring. Genvoya can harm your kidneys. This effect is increased when you also use certain other medicines, including: antivirals, chemotherapy, injected antibiotics, medicine for bowel disorders, medicine to prevent organ transplant rejection, and some pain or arthritis medicines including aspirin, Tylenol, Advil, and Aleve. Keep alfuzosin HCl extended-release tablets and all medicines out of the reach of children. where to purchase alavert uk



Pain or burning when you urinate

Alfuzosin hydrochloride extended-release tablets exhibit linear kinetics following single and multiple dosing up to 30 mg. Steady-state plasma levels are reached with the second dose of alfuzosin hydrochloride extended-release tablets administration. HCl extended-release tablets. As with other alpha adrenergic antagonists, there is a potential for syncope. Patients should be warned of the possible occurrence of such events and should avoid situations where injury could result should syncope occur. The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your not to work correctly. These are possible, but not always occur. Your doctor or can often prevent or manage interactions by changing how you use your medications or by close monitoring. Taking amiodarone with other agents that can affect your heart rhythm may increase your risk of an irregular heartbeat, which may be life-threatening. Phosphodiesterase-5 PDE5 Inhibitors: PDE5-inhibitors are also vasodilators. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding. This leaflet summarizes the most important information about alfuzosin hydrochloride extended-release tablets. If you would like more information, talk with your doctor. You can ask your doctor or pharmacist for information about alfuzosin hydrochloride extended-release tablets that is written for health professionals. Aprepitant: May increase the serum concentration of CYP3A4 Substrates. HCl extended-release tablets, and at a higher incidence than that of the placebo group. In general, the adverse reactions seen in long-term use were similar in type and frequency to the events described below for the 3-month trials. Hepatic Impairment: The pharmacokinetics of UROXATRAL have not been studied in patients with mild hepatic impairment. If you begin to feel dizzy or lightheaded, lie down with your legs and feet up. If your symptoms do not improve call your doctor. For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products. Highest Risk QTc-Prolonging Agents: QTc-Prolonging Agents Indeterminate Risk and Risk Modifying may enhance the QTc-prolonging effect of Highest Risk QTc-Prolonging Agents. Management: Avoid such combinations when possible. Use should be accompanied by close monitoring for evidence of QT prolongation or other alterations of cardiac rhythm. Genvoya is a tablet containing a combination of cobicistat, elvitegravir, emtricitabine, and tenofovir. Cobicistat reduces the action of enzymes in your liver that break down certain antiviral medicines. This allows the antiviral medicines to be used more safely and effectively at lower doses. Elvitegravir, emtricitabine and tenofovir are antiviral medicines that prevent HIV human immunodeficiency virus cells from multiplying in your body. HIV can cause acquired immunodeficiency syndrome AIDS. Alfuzosin is a selective antagonist of post-synaptic alpha 1-adrenoreceptors, which are located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra. Alpha1-Agonists: Alpha1-Blockers may diminish the vasoconstricting effect of Alpha1-Agonists. Similarly, Alpha1-Agonists may antagonize Alpha1-Blocker vasodilation. lloyds pharmacy herbal pristiq pristiq



Alfuzosin adult dosage

McVary says. So by eating a -healthy diet and being active, you may be able to stave off sexual problems. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug, changing your diet or commencing any course of treatment. Protect form light and moisture. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. These effects can occur even if grapefruit is not consumed at the same time of the silodosin dose. This interaction may occur at any time in your treatment with silodosin if grapefruit or grapefruit juice is consumed. Let your doctor know if you have any problems with dizziness, fatigue, or fainting. Complete the What is a document? See FDA-approved patient labeling. Store at room temperature between 59-86 degrees F 15-30 degrees C away from light and moisture. Protect from freezing. not store in the bathroom. Keep all medicines away from children and pets. The effect of 10 mg and 40 mg alfuzosin on QT interval was evaluated in a double-blind, randomized, placebo and active-controlled moxifloxacin 400 mg 4-way crossover single dose study in 45 healthy white male subjects aged 19 to 45 years. The QT interval was measured at the time of peak alfuzosin plasma concentrations. The 40 mg dose of alfuzosin was chosen because this dose achieves higher blood levels than those achieved with the co-administration of alfuzosin HCl extended-release tablets and ketoconazole 400 mg. Table 3 summarizes the effect on uncorrected QT and mean corrected QT interval QTc with different methods of correction Fridericia, population-specific and subject-specific correction methods at the time of peak alfuzosin plasma concentrations. No single one of these correction methodologies is known to be more valid. dutasteride



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Bayer Australia Limited November 2, 2006. Alfuzosin hydrochloride extended-release tablets are a prescription medicine that is called an "alpha-blocker". Alfuzosin hydrochloride extended-release tablets are used in adult men to treat the symptoms of benign prostatic hyperplasia BPH. Alfuzosin hydrochloride extended-release tablets may help to relax the muscles in the prostate and the bladder which may lessen the symptoms of BPH and improve urine flow. When this happens, you might also see light flashes along with the or a dark shadow come across the edge of your sight. Early symptoms of lactic acidosis may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired. Inform your doctor if your symptoms persist or worsen. See Drug Reference for a full list of side effects. Drug Reference is not available in all systems. See "What is the most important information I should know about alfuzosin HCl extended-release tablets? Surgery can help reduce BPH symptoms, but it may lead to long-term sexual complications. Middleton B, Bates DW. High-priority drug-drug interactions for use in electronic health records. GJ, Roden DM, Zareba W. Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. Woosley RL, Romero KA. www. The effect of 10 mg and 40 mg alfuzosin on QT interval was evaluated in a double-blind, randomized, placebo and active-controlled moxifloxacin 400 mg 4-way crossover single dose study in 45 healthy white male subjects aged 19 to 45 years. The QT interval was measured at the time of peak alfuzosin plasma concentrations. The 40 mg dose of alfuzosin was chosen because this dose achieves higher blood levels than those achieved with the co-administration of UROXATRAL and ketoconazole 400 mg. Table 3 summarizes the effect on uncorrected QT and mean corrected QT interval QTc with different methods of correction Fridericia, population-specific and subject-specific correction methods at the time of peak alfuzosin plasma concentrations. No single one of these correction methodologies is known to be more valid.



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Studies have shown a connection between and ED. There are many reasons why people have trouble taking their medicine. Call your doctor if you get any side effect that bothers you. Rilmenidine: Alpha1-Blockers may enhance the hypotensive effect of Rilmenidine. Lifelong vision problems can be avoided if a lazy eye is detected and treated during early childhood. Treatment includes corrective glasses or contact lenses and using a patch or other strategies to make a child use the lazy eye. What are the possible side effects of alfuzosin hydrochloride extended-release tablets? aciphex purchase now mastercard australia



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The following adverse reactions have been identified during post approval use of UROXATRAL. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Testing for blood pressure changes or orthostatic hypotension was conducted in three controlled studies. If you take too much alfuzosin HCl extended-release tablets call your local poison control center or emergency room right away. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? The recommended dosage is one 10 mg UROXATRAL alfuzosin HCl extended-release tablet once daily. The extent of absorption of alfuzosin is 50% lower under fasting conditions. Therefore, Uroxatral should be taken with food and with the same meal each day. The tablets should not be chewed or crushed. Cardura doxazosin hydrochloride US prescribing information. Alfuzosin hydrochloride extended-release tablets can cause a painful erection priapism which cannot be relieved by having sex. If this happens, get medical help right away. If priapism is not treated, you may not be able to get an erection in the future. miter.info finasteride



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If in infants and children, treatment needs to be sought immediately. Side effects may go away after you take the medicine for a while. Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for healthcare professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience and judgment in diagnosing, treating and advising patients. Read the Patient Information that comes with alfuzosin HCl extended-release tablets before you start using it and each time you get a refill. There may be new information. This leaflet does not take the place of talking with your doctor about your condition or your treatment. You and your doctor should talk about all your medicines, including alfuzosin HCl extended-release tablets, now and at your regular checkups. Some products that may interact with this drug include: other alpha blocker drugs such as prazosin, terazosin. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. This leaflet summarizes the most important information about alfuzosin HCl extended-release tablets. If you would like more information, talk with your doctor. You can ask your doctor or pharmacist for information about alfuzosin HCl extended-release tablets that is written for health professionals. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Who should not take UROXATRAL? Caution is advised when alpha adrenergic antagonists, including alfuzosin HCl extended-release tablets, are coadministered with PDE5 inhibitors. Alpha adrenergic antagonists and PDE5 inhibitors are both vasodilators that can lower blood pressure. Cialis tadalafil UK summary of product characteristics. zoloft



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What conditions does alfuzosin treat


Does alfuzosin interact with other medications

The cornea is the clear, dome-shaped "window" at the front of your eye. May cause orthostatic hypotension and syncope within a few hours following administration; anticipate a similar effect if therapy is interrupted for a few days, if dosage is rapidly increased, or if another antihypertensive drug, PDE-5 inhibitors, or nitrates is introduced. Use with caution in patients with symptomatic orthostatic hypotension. CYP3A4 Inducers Strong: May increase the metabolism of CYP3A4 Substrates. Management: Consider an alternative for one of the interacting drugs. Some combinations may be specifically contraindicated. Consult appropriate manufacturer labeling.

Alfuzosin dosing information

Alfuzosin belongs to a class of drugs known as alpha blockers. The tablet also contains the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, hypromellose, hydroxypropyl cellulose, magnesium stearate, microcrystalline cellulose, povidone, talc and yellow ferric oxide. Uroxatral alfuzosin hydrochloride US prescribing information. Sanofi-Synthelabo, Inc. May, 2013. Phosphodiesterase 5 Inhibitors: May enhance the hypotensive effect of Alpha1-Blockers. Management: Ensure patient is stable on one agent prior to initiating the other, and always initiate combination using the lowest possible dose of the drug being added. When tadalafil is used for treatment of BPH, concurrent alpha 1-blockers are not recommended.

Alfuzosin forms and strengths

This happens when your eyes can't make enough good-quality tears. TURP transurethral resection of the prostate has been linked to ejaculation problems and erectile dysfunction. It's not clear why, says New York urologist Alex Shteynshlyuger, but there is an association. Viagra sildenafil Australian prescribing information.

General information about alfuzosin

This is the name for a group of diseases that cause inflammation of the uvea. Discuss the risks and benefits with your doctor. Should overdose of alfuzosin HCl extended-release tablets lead to hypotension, support of the cardiovascular system is of first importance. Restoration of blood pressure and normalization of heart rate may be accomplished by keeping the patient in the supine position. If this measure is inadequate, then the administration of intravenous fluids should be considered. If necessary, vasopressors should then be used, and the renal function should be monitored and supported as needed. Alfuzosin is 82% to 90% protein bound; therefore, dialysis may not be of benefit.

If you take too much UROXATRAL call your local poison control center or emergency room right away. Talk to your doctor about using alfuzosin safely. HCl extended-release tablets concomitantly with anti-hypertensive medication and nitrates. Care should be taken when alfuzosin HCl extended-release tablets are administered to patients with symptomatic hypotension or patients who have had a hypotensive response to other medications. If you notice a sudden change in the type or number of spots or flashes you see or a new dark “curtain" in your peripheral vision, go to your eye doctor as soon as possible.

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